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Store-A-Tooth™ Dental Stem Cell Banking and Product News

Provia Laboratories™ Brings on New Stem Cell and Biobank Business Development Executive

Posted by Ryan LeClair on Mon, Sep 14, 2015 @ 10:00 AM

Provia Laboratories, a leader in stem cell processing and biobanking, appoints Timothy Beals as its new Senior Director, Business Development. Provia seeks to leverage its cGMP laboratory capabilities and biobank facility into new research opportunities, expanded stem cell processing and commercial biobanking services, as well as further international expansion.

Timothy Beals, Senior Director, Business Development Provia LaboratoriesLittleton, MA (September 14, 2015): Provia Laboratories announced today that Timothy Beals joined Provia as the Senior Director, Business Development. Provia, who offers Store-A-Tooth™, a service to preserve the stem cells from healthy extracted teeth, recently completed a multi-million dollar investment in launching a new cGMP stem cell processing laboratory and storage facility in Littleton, MA. Combined with the reputation Store-A-Tooth developed as the leader in dental stem cell banking, Provia is poised to leverage their expertise and new cGMP facility to pursue biomedical research, cell processing beyond dental stem cells, commercial bio-banking services, and international expansion.

Beals’ career spans over a period of 30 years as a regional, national and international cryopreservation specialist, and a seasoned executive focused on developing, launching and managing stem cell companies and bio-banks worldwide. He has been involved in cord blood, dental, synovial, adipose and amniotic fluid stem cell processing and banking for both clinical and research applications. With a strong understanding of the emerging and maturing needs of the clinical and research stem cell industry, Beals will lead Provia Laboratories efforts in developing additional opportunities and strategic growth.

“We are very fortunate to have Tim join our management team,” said Howard Greenman, CEO of Provia Laboratories. “I’ve known Tim for over a decade, his experience, reputation, network, commitment and insight are exactly what Provia needs to grow and advance our role in this rapidly growing field.”

“I recall over 10 years ago when the Provia team contacted me to discuss needs relating to cryopreservation of stem cells from teeth,” Beals added. “At that time it was not commonly heard of, but the Provia team became early pioneers, and developed the opportunity into a rapidly growing business for Store-A-Tooth. It has been exciting to witness their growth, success and recognition in this field. This is an exciting time and opportunity for all of us here at Provia Laboratories.”

The proper collection, transport, processing, testing and preservation of stem cells is a crucial and significant part of the regenerative medicine value chain. Companies have provided stem cell banking services from bone marrow, and umbilical cord blood for over two decades. More recent discoveries in the past 10 years identified additional sources of valuable stem cells derived from dental pulp, adipose and other sources. Tissues that have commonly been discarded as biological waste contain valuable tissue forming stem cells called mesenchymal stem cells, and have shown to generate growth and repair of bone, cartilage, tendon, nerve and heart tissue. Thousands of patients have been treated with stem cells and well over a million families have privately preserved stem cells for their families’ own future use. 

About Provia Laboratories, LLC

Provia Laboratories, LLC (http://www.provialabs.com) is a healthcare company headquartered in Littleton, MA which specializes in high-quality biobanking. Provia offers a variety of products and services for use in complex biobanking environments to improve sample logistics, security, and quality. The company advises industrial, academic, and governmental clients on matters related to the preservation of biological specimens for research and clinical use. Provia’s core business, Store-A-Tooth (http://www.store-a-tooth.com) is a private stem cell bank with nearly 1000 collection sites serving clients from around the world.

Tags: Company Updates

Simply Smiles Miami in Pinecrest, FL has partnered with Store-A-Tooth

Posted by Ryan LeClair on Wed, Sep 09, 2015 @ 10:55 AM

Store-A-ToothTM is proud to announce Dr. Alexander Trujillo and Dr. Kiara Miro-Trujillo as our newest dental partners in Miami, Florida

Simply Smiles Miami

As our dental partners, Dr. Alexander Trujillo and Dr. Kira Miro-Trujillo will work with Provia Labs, providers of the Store-A-Tooth private stem cell banking service, to educate patients who request to learn more about banking their dental stem cells.

A growing body of medical research is focused on the use of stem cells to heal tissue damaged through injury, disease, aging or congenital defect. 

Since the discovery of stem cells in dental pulp, patients losing teeth, either baby teeth or extracted adult teeth, have been choosing to preserve (bank) those stem cells for their personal use in the future. 

Watch the 2-minute video below to learn more about dental stem cell banking:


 

About Simply Smiles:

Dr. Kiara R. Miro-Trujillo
 earned her dental degree from New York University College School of Dentistry. She is a member of the American Dental Association and Florida Dental Association. Her area of interests are Cosmetic Dentistry and Pediatrics. She has two beautiful sons, with whom she enjoys spending her free time. She also serves the community by volunteering in Community Smiles, a non profit dental clinic that provides dental care for families with low income. 
Along with her husband, Alexander, they participate in their local church as missionaries to provide dental care to those in need abroad.

Dr. Alexander D.Trujillo received his Doctor of Dental Surgery degree (DDS) at Universidad Central del Este in Dominican Republic in 1997 and his DDS degree from New York University College of Dentistry in 2004. Dr. Trujillo began his private practice career in June of 2004 and since then has dedicated his practice to complete dental restoration. Dr. Trujillo has been certified by the State of Florida in I.V. Conscious Sedation and has received a certificate in Implant Dentistry. He is a member of the Florida Dental Association, which helps him keep current in all matters related to dentistry. Dr.Trujillo is also an active member of the dental community, participating with local charities providing dental services within state as well as abroad to others in need. He has traveled to Haiti and Guatemala to provide dental care for both adults and children. Dr. Trujillo is an active member of New Life Ministries, a local Christian church. He is the chairman of the church’s Golf tournament committee and is intimately involved with Hands of God ministries, New Life’s missions team. In his spare time he loves to spend time with his lovely wife, Kiara and his four sons. His hobbies include: traveling, exercise, fishing and diving. 

Tags: Company Updates

Advanced Oral and Maxillofacial Surgery (AOMS) in Elmhurst, IL Partners with Provia Labs to make Store-A-Tooth™ Dental Stem Cell Banking Available to their Patients.

Posted by Ryan LeClair on Mon, Jun 29, 2015 @ 10:00 AM

Advanced Oral & Maxillofacial Surgery

Together, Advanced Oral and Maxillofacial Surgery and Provia Laboratories aim to ensure every AOMS patient is informed about Store-A-Tooth and given the choice to preserve their own stem cells for future regenerative medicine.

Littleton, MA (July 29, 2015):
Nearly everyone has heard of the potential of stem cells to treat a wide range of serious diseases. Yet few people realize that a rich source of these cells is teeth—baby teeth that come loose during childhood, wisdom teeth extracted from teens or young adults, and teeth that need to be pulled to make room for braces. These potent stem cells exist in the dental pulp of healthy teeth, and as long as they are collected, transported, processed and stored properly, they can be preserved to protect a family’s future health. 

Provia Laboratories offers a service to do just that and it is called Store-A-Tooth. The Littleton, MA based company manages an FDA Registered, GMP tissue bank preserving stem cells for thousands of families. Only recently has Store-A-Tooth been introduced in the Greater Chicagoland area – part of a national expansion of Provia’s widely popular Store-A-Tooth service.

Advanced Oral and Maxillofacial Surgery in Elmhurst, IL offers a full scope of oral and maxillofacial surgery services including IV anesthesia, dental implants, and dental extractions – including wisdom teeth. They pride themselves on offering kind, compassionate care in a comfortable setting. “AOMS is a perfect partner to work with. They are committed to high quality care and ensuring their patients are well informed of the latest technologies and options,” says Howard Greenman, Chief Executive Officer of Provia Laboratories. He continues, “Most families are unaware of these important cells that would normally be discarded. The Oral Surgery community plays a vital role in helping families make informed decisions before it is too late.”

Advanced Oral and Maxillofacial Surgery will participate in the Store-A-Tooth program by making information about the service available to their patients. Store-A-Tooth is an affordable option for families seeking to make their children’s stem cells available for them in the future. For more information about Store-A-Tooth™ dental stem cell banking, please call 1-877-867-5753, visit us at http://www.store-a-tooth.com ,or ‘Like’ Store-A-Tooth at http://www.facebook.com/storeatooth.

About Provia Laboratories, LLC

Provia Laboratories, LLC (http://www.provialabs.com) is a healthcare company headquartered in Littleton, MA which specializes in high-quality biobanking. Provia offers a variety of products and services for use in complex biobanking environments to improve sample logistics, security, and quality. The company advises industrial, academic, and governmental clients on matters related to the preservation of biological specimens for research and clinical use. Provia’s core business, Store-A-Tooth (http://www.store-a-tooth.com) is a private stem cell bank with nearly 1000 collection sites serving clients from around the world.

Tags: Company Updates

Appell Dental Group Offers Dental Stem Cell Banking

Posted by Ryan LeClair on Mon, Mar 23, 2015 @ 03:38 PM

Appell Dental Group

 

AppellLogo

Store-A-Tooth is proud to announce Appell Dental Group in Arlington Heights, IL as our newest dental partner.

As our dental partner, Appell Dental Group in Arlington Heights, IL will work with Provia Labs, providers of the Store-A-Tooth private stem cell banking service, to educate patients who request to learn more about banking their dental stem cells.

A growing body of medical research is focused on the use of stem cells to heal tissue damaged through injury, disease, aging or congenital defect. Since the discovery of stem cells in dental pulp, patients losing teeth, either baby teeth or extracted adult teeth, have been choosing to preserve (bank) those stem cells for their personal use in the future. 

Watch our two minute video below to learn more about the valuable stem cells in teeth. 

 

Tags: Company Updates

North Shore Oral and Maxillofacial Surgery Offers Dental Stem Cell Banking

Posted by Ryan LeClair on Thu, Feb 19, 2015 @ 03:51 PM

NorthShoreCropped resized 600

Store-A-Tooth is proud to announce North Shore Oral and Maxillary Surgery as our newest dental partner.

As our dental partner, North Shore Oral and Maxillofacial Surgery in Buffalo Grove, IL will work with Provia Labs, providers of the Store-A-Tooth private stem cell banking service, to educate patients who request to learn more about banking their dental stem cells.

A growing body of medical research is focused on the use of stem cells to heal tissue damaged through injury, disease, aging or congenital defect. Since the discovery of stem cells in dental pulp, patients losing teeth, either baby teeth or extracted adult teeth, have been choosing to preserve (bank) those stem cells for their personal use in the future. 

Watch our two minute video below to learn more about the valuable stem cells in teeth.


Tags: Company Updates

Stem Cells, Biobanking and the Shift to Precision Medicine

Posted by James Andrews on Thu, Dec 26, 2013 @ 10:06 AM

With a major paradigm shift underway related to diagnostics, treatments and delivery options, the shape of medical technology is changing rapidly to an approach that is much more patient-centered and focused on “precision medicine,” said Dr. Joseph Laning, Vice president of Research and Development for Provia Laboratories, LLC, during a presentation at the NSTC Biosciences seminar held on November 1 at Cummings Center in Beverly. “This change brings opportunity related to physician training, medical record portability and availability, as well as new and more accurate diagnostics – all leading to more personalized medicine.”

how stem cells can potentially be used as tools for basic research and drug discoveryDuring his presentation, Dr. Laning described how stem cells can potentially be used as tools for basic research and drug discovery, and how in the future “it could be your banked materials for you and your family” that are used in targeted medical treatments when needed. Dr. Laning outlined available sources for stem cells – including adult, embryonic, and induced – and provided an overview of the economic and ethical issues associated with each source and the use of stem cells in general.  He also outlined current pre-clinical and clinical testing being conducted in the field – including studies focusing used on stroke, spinal cord injuries, and regenerative medicine.

Stem cells are versatile self-contained models and are a reproducible source material for both basic and applied research, Dr. Laning told seminar attendees. For these reasons and because the “near and long-term clinical benefits are potentially immense,” there is an important value proposition associated with the use of stem cells in both biobanking and clinical research, he said. “We will see stem cells become state-of-the-art testing platforms and achieve therapeutic value,” Dr. Laning predicted. In order for this to happen, he said a company or group will need to “step up and push forward” some of the current and proposed clinical trials related to stem cells – then this will help drive momentum as well as product availability and increased interest.

Dr. LaningDr. Laning, now with Provia Labs, has spent the past 18 years seeking to translate concepts into products in the fields of wound care, regenerative medicine, and stem cell therapy. With a bachelor’s degree in Biology from Boston University and a PhD in Immunology from Harvard, Dr. Laning is currently targeting research related to the optimization of dental sourced biobanking methods. Lexington-based Provia Labs is a health services company specializing in high quality stem cell biobanking, including the Store-A-Tooth™ service which provides an opportunity for parents to preserve stem cells from baby and wisdom teeth in preparation for future advances in stem cell therapies.

The seminar was sponsored by Lisa Miranda, President and CEO of BioBusiness Consulting, Inc., which specializes in biobanking, clinical research, and biotechnology product development advisory. Biobusiness Consulting, a boutique consulting firm based in the Greater Boston Area, serves pharmaceutical, biotech, academic and government sectors worldwide. For more information please contact Lisa Miranda @ lisabmiranda@biobusinessconsulting.com

Republished courtesy of The North Shore Technology Council http://nstc.org

Tags: Dental Stem Cells, Research, Healthcare, Regenerative Medicine, Company Updates, Adult Stem Cells

Stem cell therapy on course to help treat spinal cord injuries

Posted by James Andrews on Thu, Dec 19, 2013 @ 10:07 AM

Adult stem cell treatment for spinal cord injuriesA systematic survey of the scientific literature shows that stem cell therapy can have a statistically significant impact on animal models of spinal cord injury, and points the way for future studies.

Spinal cord injuries are mostly caused by trauma, often incurred in road traffic or sporting incidents, often with devastating and irreversible consequences, and unfortunately having a relatively high prevalence (250,000 patients in the USA; 80% of cases are male). High-profile campaigners like the late actor Christopher Reeve, himself a victim of sports-related spinal cord injury, have placed high hopes in stem cell transplantation.

But how likely is it to work?

This question is addressed in a paper published 17th December in the open access journal PLOS Biology by Ana Antonic, David Howells and colleagues from the Florey Institute and the University of Melbourne, Australia, and Malcolm MacLeod and colleagues from the University of Edinburgh, UK.

Stem cell therapy aims to use special regenerative cells (stem cells) to repopulate areas of damage that result from spinal cord injuries, with the hope of improving the ability to move ("motor outcomes") and to feel ("sensory outcomes") beyond the site of the injury. Many studies have been performed that involve animal models of spinal cord injury (mostly rats and mice), but these are limited in scale by financial, practical and ethical considerations. These limitations hamper each individual study's statistical power to detect the true effects of the stem cell implantation.

This new study gets round this problem by conducting a "meta-analysis" – a sophisticated and systematic cumulative statistical reappraisal of many previous laboratory experiments. In this case the authors assessed 156 published studies that examined the effects of stem cell treatment for experimental spinal injury in a total of about 6000 animals.

Overall, they found that stem cell treatment results in an average improvement of about 25% over the post-injury performance in both sensory and motor outcomes, though the results can vary widely between animals. For sensory outcomes the degree of improvement tended to increase with the number of cells introduced – scientists are often reassured by this sort of "dose response", as it suggests a real underlying biologically plausible effect.

The authors went on to use their analysis to explore the effects of bias (whether the experimenters knew which animals were treated and which untreated), the way that the stem cells were cultured, the way that the spinal injury was generated, and the way that outcomes were measured. In each case, important lessons were learned that should help inform and refine the design of future animal studies. The meta-analysis also revealed some surprises that should provoke further investigation – there was little evidence of any beneficial sensory effects in female animals, for example, and it didn't seem to matter whether immunosuppressive drugs were administered or not.

The authors conclude: "Extensive recent preclinical literature suggests that stem cell-based therapies may offer promise; however the impact of compromised internal validity and publication bias means that efficacy is likely to be somewhat lower than reported here."

Potential "Biological Insurance"

For decades, doctors have harnessed the unique ability of stem cells to treat leukemia and genetic blood diseases. But now, researchers are discovering that these cells have the power to heal, to fight disease, and to regenerate damaged or aging tissue throughout the body. To fully understand why they hold the potential to change your child’s medical future, get to know more about stem cells.

Stem Cell Basics

Ordinary cells in your body replicate to make new cells of the same type - blood cells make more blood cells, skin cells make more skins cells and so on. However, there is another type of cell, called a stem cell.

Stem cells are able to repair or replace damaged tissue. This is why scientists and doctors are so excited about the growing role of stem cells to treat disease, injury, and the deterioration of tissue due to aging. Amazingly, after our birth and into adulthood, we keep a store of these stem cells in certain parts of our body.

Mesenchymal Stem Cells

Different types of stem cells exist in different body tissues, and in varying concentrations. One of the most well-understood and widely researched types of stem cells is the mesenchymal stem cell.

Mesenchymal stem cells can form tissues such as bone, nerve, muscle, and blood vessels. They also help body tissue to repair itself, and they play an important role in healing by suppressing inflammation.

Though located in a number of places in the body, mesenchymal stem cells can be found in especially high concentrations in the healthy dental pulp of teeth.
e.

Mesenchymal Stem Cells From Teeth Have Helped Paralyzed Animals Walk Again.

Diseases and injury to the nervous system affect millions of people of all ages, and scientists are actively exploring the use of stem cells to re-grow or repair nerve tissues and cells (a process known as neuroregeneration).

Today there is no cure for spinal cord injury, a misfortune that can strike at a moment’s notice with devastating effect on the person injured as well as their family.

Researchers have been studying the use of stem cells to treat spinal cord injury for many years. Recently, a research team at Nagoya University in Japan demonstrated that stem cells from teeth – both baby teeth and wisdom teeth – helped heal spinal cord injuries in rats and even restored some ability to walk. Another important finding: the stem cells from teeth worked better than stem cells from bone marrow.

Younger Is Better

Over time, even stem cells succumb to the environmental “insults” that age all of our cells. Freezing cells in a youthful state preserves their future ability to generate replacement tissue and heal the body.

All of these attributes make stem cells the cornerstone of the emerging field of treatments and therapies called Regenerative Medicine.

You can now bank on them

Store-A-Tooth is a simple service that takes that wisdom tooth or baby tooth that would be thrown out as biological waste by your dentist and banks it for you for the future.

Find out more: http://www.store-a-tooth.com/why-bank-stem-cells

 

Tags: Dental Stem Cells, Research, Healthcare, Regenerative Medicine, Company Updates, Adult Stem Cells

The keys to a successful healthcare business

Posted by James Andrews on Fri, Nov 22, 2013 @ 09:24 AM

Investment life article on the business of stem cellsBuilding a healthcare business is very hard. It takes more than a needed technology.  It takes more than a top-notch team.  Healthcare businesses, particularly life science businesses, require a considerable amount of capital for both product development and market development.

An interview with Provia Laboratories CEO Howard Greenman, highlights the difficulties and keys to success when building a healthcare business from the ground up:

I remember 14 years ago, I was sitting across the table from a healthcare venture capitalist – pitching my first startup company.  It was the first time I was in such a meeting and I was nervous – very similar to the TV show Shark Tank.  I will never forget what he said:  “There are many great healthcare ideas, but few that are good business ideas.”  He continued, “I measure the potential of a healthcare innovation first by its finance-ability.”  It seems a shame that many interesting healthcare innovations that are needed by patients don’t make it to market because they don’t make sense to investors.

My current company, Provia Laboratories has a technology (the ability to collect, transport, process, expand, test, and preserve the valuable adult stem cells found inside baby and wisdom teeth) that is both an incredible technology for patients allowing them to preserve their youthful stem cells for future therapies, but it is also an appealing business for investors.  This is described in the attached article about our investment partner – Grace Century.

We are fortunate to be working with such an outstanding firm who selected Provia Laboratories as a “game changer” investment for its portfolio.  Grace Century has done a rigorous job evaluating our business through their due diligence process and continues to provide advice and support to us as a true partner.  We have a needed technology, a world-class team, and an amazing investment partner providing us the needed capital to grow.

Article on investing in stem cell storage

Here is an excerpt from an article in Investment Life magazine:

Stem Cells and Investment Strategy

How a select group of investors is identifying opportunity in an increasingly complex environment.

To paraphrase Ralph Waldo Emerson - if you build a better mousetrap, the world wil beat a path to your door.
It appears that a company called Grace Century FZ, LLC has invented the equivalent of a better mousetrap. This organization's approach to providing exceptional investment value for clients is based on the identification of opportunities within some of the fastest growing sectors in the world...

...One of the current investment opportunities identified by Grace Century fulfills all of the above criteria (common sense, a workable solution, the right team and the right risk-reward ratio). The investment opportunity is a company called Provia Laboratories, which has a branded service name 'Store-A-Tooth' (stem cell storage).

Stem Cell Storage
Ongoing research indicates that stem cells may hold the key to repairing organs, curing chronic disease and even extreme human longevity.

For this reason many parents are storing umbilical cord material which can be used in host-specific therapy.

What of parents who did not store umbilical material? One company - Provia - thinks they might have a solution.

You can read the entire article here:
http://issuu.com/panashcomedia/docs/ilm_issue_november_december_2013

Additional links:
More information on the Store-A-Tooth™ service provided by Provia Laboratories

Tags: Dental Stem Cells, Research, Healthcare, Regenerative Medicine, Company Updates, Stem Cells & Diabetes, Adult Stem Cells

The Tooth Fairy May Soon Be Unemployed

Posted by Marissa Oneill on Wed, Apr 10, 2013 @ 03:36 PM

Think twice before giving the Tooth Fairy that crisp dollar. Your child's tooth is worth way more. Teeth contain stem cells and those cells can potentially be the key to unlocking treatments and therapies for many serious conditions and diseases.

If you missed the opportunity to bank your child's cord blood, at a cost of around $2,000, you can still bank your child's stem cells from baby teeth, orthodontia, or wisdom teeth extractions. The dental pulp inside those teeth contain stem cells that regenerate into several different kinds of cells -- like neurons, bone, cartilage, and certain cardiac cells to repair damaged heart tissue. 

If you missed the opportunity to bank your child's cord blood, at a cost of around $2,000, you can still bank your child's stem cells from baby teeth, orthodontia, or wisdom teeth extractions. The dental pulp inside those teeth contain stem cells that regenerate into several different kinds of cells -- like neurons, bone, cartilage, and certain cardiac cells to repair damaged heart tissue. 

Instead of having your dentist discard these powerful stem cells, or putting them under the pillow for the Tooth Fairy - consider how dental stem cells could one day help protect your family's health. Your dental professional can become a provider in one easy, free step.

 

                

This month, Austin Considine of Motherboard Vice Media writes:

“Unfortunately, most of the one million Americans affected by the condition and the 15,000 children newly diagnosed each year missed the opportunity to bank stem cells from their cord blood when they were born,” said Howard Greenman, chief executive for Provia, in a company press release. According to that press release, the company donates “up to 50 percent” of its proceeds to diabetes research.

Provia bills its service—called “Store-A-Tooth”—as an alternative to cord blood banking that not only offers parents a bigger window, but is slightly cheaper. I called the company using the number on the website to get a few more details about pricing and how it works.

For $649, Provia does what’s called a “whole tissue” preservation. That basically means you ship them your freshly plucked tooth or teeth, the lab extracts the soft tissue inside and immediately puts it in a cryo-protective solution so the tissue can be frozen for future use."

Teeth are simply extracted by a dental professional or in your home (the whole tying your tooth to a doorknob trick), fresh samples with pulp are a must, and Store-A-Tooth provides a safe kit for overnight transport to their lab. Simple, easy, effective.

Read more about us this month in "Back Off, Tooth Fairy, Those Baby Teeth May One Day Save a Life"...

Protect your family's future health by banking your children's stem cells in teeth today. The Tooth Fairy will just have to find another job.

 




Tags: Dental Stem Cells, Healthcare, Regenerative Medicine, Company Updates, Adult Stem Cells

Top Stem Cell Stories of 2012

Posted by Marissa Oneill on Tue, Jan 01, 2013 @ 03:47 PM

A review of Stem cells in 2012Another year passed. Another year present.

2012 was quite a big year for stem cells news so let's recap its monumental progress for regenerative therapies for conditions such as diabetes, spinal cord injury, and Alzheimer's disease as presented by the California Institute for Regenerative Medicine (CIRM).

 

1.) Store-A-Tooth launched its "Store a Tooth - Find a Cure" initiative earlier this year with its mission to fund diabetes research and support the potential of stem cells therapies in treating the disease. Amongst some of our initiative efforts were our attendance of the annual Children with Diabetes Conference 2012 in Orlando as well as our participation of sponsorship of the Juvenile Diabetes Research Foundation Boston Walk to Cure Diabetes. 

CIRM released a short video interview of Chris Stiehl and Sarah Young, both living with type 1 diabetes, along with Kevin D'Amour, Chief Scientific Officer at Viacyte, Inc., which was recently awarded a $20 million award to help bring an embryonic stem cell-based diabetes therapy to clinical trials. The video gives great insight into a day in the life of someone struggling with the disease and emphasizes the exciting potential and hope for such stem cell therapies to finally arise ultimately leading to a cure.

 

Find out how stem cells in teeth are being used to find a cure for diabetes here

2.) In June, CIRM grantee Irv Weissman at Stanford University wrote a bold article about the barriers that confront the development new therapies. He proceeds to express his frustration with fraudulent stem cell clinics, the lack of FDA presence, private cord blood banks, incomplete biological models of diseases, poor science, and problematic business development practices. 

He expresses an urgency for stem cell therapies and their potential to revolutionize medicine:

"Remember, right now our patients, friends, and families are contracting diseases that have a very short window of opportunity in which regenerative therapies can save them, and each delay removes a cohort of them from possible cures. We should not fail them."

Read Irv's complete article here

3.) The third story describes an interview with Katie Sharify, the fifth stem cell trial participant of Gerson's CIRM-supported now closed clinical trial for spinal cord injury. Geron’s was the first clinical trial to test a therapy based on embryonic stem cells. Katie, confined to a wheelchair after an accident, describes what it’s like to be a patient in a stem cell clinical trial. She expresses how she had very little understanding of the science before her injury and had very little time to get as informed as possible before making a decision about whether or not to participate. She was fortunate enough to quickly educate herself in just six days and she needed to educate her parents, who barely speak English, while also adjusting to life in a wheelchair. 

       “I was part of something that was bigger than me, and bigger than all of you.”

Although Geron terminated the trial, Geron entered into a nonbinding agreement to transfer their embryonic stem cell programs to BioTime, Inc. A lot of unknowns remain in that agreement, but if it goes through it could mean that more people with recent spinal cord injuries have a chance to make a decision like Katie’s. 

 

Find out how stem cells in teeth are being used to treat spinal cord injury here


4.) The fourth top topic at CIRM was their discussion with CIRM grantee Lawrence Goldstein about stem cell therapies for Alzheimer’s disease. As part of that conversation, they discussed what he saw in the future for stem cell science. He realizes some stem cell projects may never go forward and progress, but  “some of them are going to hit it big and change everything.” He supports the potential and great promise the future of regenerative medicine holds such that "if the public continues to adequately fund research with stem cells we will see breakthroughs that are absolutely unexpected and that will change the way that we deliver medicine."

 

 

5.) In September of 2012, StemCells Inc reported huge news that two patients in their clinical trial for spinal cord injury were recovering well and seemed to have gained some sensation. The preliminary success of this trial allowed the patients to feel touch and heat and although this news is very exciting, the data has yet to be reviewed by scientists and published, and also the data reported only pertains to three people. To gain a more definitive conclusion, the scientists will need to perform trials on a larger number of spinal cord injury patients.

However, this is still exciting news that offers promise for some even in the smallest ways, especially those confined to a wheelchair due to a spinal cord injury. It emphasizes the world of difference the future of regenerative medicine exemplifies and how stem cells in bone marrow, cord blood and teeth can one day be used to treat spinal cord injury.

 

Big things in 2012, so here's to 2013!

Tags: Dental Stem Cells, Research, Healthcare, Regenerative Medicine, Company Updates, Stem Cells & Diabetes, Adult Stem Cells

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