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Adult Stem Cells To Cure Autism [VIDEO]

Posted by James Andrews on Thu, Oct 25, 2012 @ 03:45 PM

Stem Cells to 'Cure' autimsResearchers recently announced the beginning of a FDA-approved clinical trial that uses stem cells to ‘cure’ autism.

Dr. Michael Chez, director of pediatric neurology at Sutter Neuroscience Institute in Sacramento, Calif., said he and his colleagues have been processing the trial for more than a year now, and they have high hopes it will succeed.

“The data is scattered with glimmers of potential benefit.”
- Dr. Michael Chez, director of pediatric neurology at Sutter Neuroscience Institute in Sacramento, Calif.

“What we are looking at, is cases that don’t have an obvious genetic link,” Chez told FoxNews. “Patients that we presume something went wrong with their brains, which caused a change to autistic features.”

In other words, the trial’s patients will essentially have no reason to have autism – or at least no genetic markers for the disease. This means they must have presumably developed it through another factor, such as the environment or exposure to an infection.

Chez got the idea to ‘treat’ autism with cord blood stem cells when he observed the cells make a big difference for a little boy who had cerebral palsy.

Now, Chez wants to put this boy’s experience to work for children with autism.

What is Autism?

Autism is a developmental disorder that appears in a child’s first three years of life, according to the National Institutes of Health.

One in 88 U.S. children have it, and it affects one in 54 boys. The condition impacts the brain’s normal development of social and communication skills – sometimes mildly, sometimes extremely.

More children will be diagnosed with autism this year than with AIDS, diabetes and cancer combined, according to AutismSpeaks.org.

“We want to see if there is any benefit to giving them an infusion to redirect the nervous system cells, which may have programmed themselves due to a secondary factor,” Chez said. “This may work on autism on different mechanisms in theory by modifying either the immune system or modifying the nervous system by indirect or direct methods.”

Putting stem cells to work 

Chez will give 30 kids infusions of their own cord blood cells. Most of the children for the trial have already been lined up, and they have been screened to make sure they don’t have any other issues that may have caused their autism (for example, Fragile X syndrome, stroke, head injury or prematurity).

Using the child’s own stem cells will make the study safe and ethical – plus, the cells are younger and have not been exposed to environmental factors, like viruses or chemicals, which can alter the cell’s function and structure. By using the children’s own stem cells, their bodies cannot reject them.

However, in the future, a sibling’s stem cells could theoretically work.

Researchers can develop further goals when and if they see results.

“The next level of research will be to determine how that works,” Chez said.

Everyone in the pilot study will get a dose of stem cells, however; the children will be divided into two groups. Group 1 will receive an initial infusion of stem cells, while Group 2 will receive a placebo saline infusion. The groups will be observed over the course of six months, and then the groups will reverse: Group 1 will receive a dose of saline and Group 2 will receive the stem cells.

Chez is hoping to see results of the study within six weeks.

Autism studies involving stem cells are nothing new

Several autism studies have already occurred overseas.  However, they weren’t necessarily controlled studies, or the stem cells may have come from an open pool of donors.

“The data is scattered with glimmers of potential benefit,” Chez said. “There are also patients who have gone to other countries and gotten so-called stem cells on their own; and we’re getting anecdotal Internet studies that we don’t want to be misinterpreted. We want to do this in a scientific way and make sure it’s not just these parents are so hopeful, they are seeing a placebo effect.”

If the results are that dramatic and turn the children’s symptoms around rapidly, then Chez feels the stem cells will be ‘talking’ to other cells within the body, causing those cells to become more functional than dysfunctional.

“In theory, it would take more than that time for the nervous system cells to grow,” he said. “It might be more than growing tissue. It may be a simple infusion, (and) it doesn’t have to travel to your brain.”

Saving your own family's stem cells

As a parent, protecting your growing family is a top priority. You can take the first step by saving – or "banking" – your child's stem cells. It's an opportunity that can be lifesaving or life-changing for your family.

The dental pulp in teeth contains valuable stem cells that are being looked at for a variety of medical treatments.

What Makes These Stem Cells So Valuable?

Stem cells are the body's building blocks for organ tissue, blood, and the immune system. Doctors started using stem cells more than 20 years ago to treat diseases that previously had been treated with bone marrow.

Today, the primary type of stem cells in umbilical cord blood – called hematopoietic - help treat many serious illnesses and disorders. Cord blood stem cells can only be collected at birth, so it is important to make your banking decision well before your due date.

Stem Cells, in Particular, Are:

  • Smart: They "know" how to find injured cells and tissue in the body and initiate a healing process.
  • Powerful: These primary type of stem cells have the potential to cure many life-threatening illnesses. These stem cells may also be able to treat serious injuries.
  • Unique: Your child's one-of-a-kind stem cells have unique advantages over the adult stem cells found in bone marrow. They're younger, more versatile, and have not been exposed to environmental factors.

The Collection Procedure Is Safe and Easy

If your child is loosing a baby tooth, having wisdom teeth removed, or having a routine extraction for orthodontic reasons, your dentist simply places the teeth in our FDA approved device instead of discarding them as waste.

To learn more:

         Speak to a stem cell specialist                    Family stem cell info kit

Tags: Dental Stem Cells, Research, Healthcare, Regenerative Medicine, Adult Stem Cells

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